Radiation Carcinogenesis at Low Doses

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ANNEX G Biological effects at low radiation doses

I. CELLULAR EFFECTS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 77 A. DESIGNATION OF LOW DOSES AND LOW DOSE RATES . . . . . . . . . 77 1. Physical factors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 77 2. Biological approaches . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 79 B. DAMAGE TO ...

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Low Doses and Radiation Risk in vivo

The “Linear No Threshold” hypothesis, used in all radiation protection practices, assumes that all doses, no matter how low, increase risk. However, in human and other mammalian cells, low doses of low LET radiation such as gamma and X-rays induce an adaptive response that protects against both radiation-induced and spontaneous risk. An in vivo test of the hypothesis in mice showed that a 100-m...

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Radiation hormesis and adoptive response induced by low doses of limiting radiation

  Ionizing radiation has long been known to produce detrimental biological effects. Although these harmful effects are the results of high doses of exposure, some other maladies such as mutation and cancer seems  to be induced at low doses of exposure. In recent decades, however, some pioneer scientists have indicated that ionizing radiation like many other essential agents has toxic effects  ...

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Low-dose radiation exposure and carcinogenesis.

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Carcinogenesis Induced by Low-dose Radiation

Background Although the effects of high dose radiation on human cells and tissues are relatively well defined, there is no consensus regarding the effects of low and very low radiation doses on the organism. Ionizing radiation has been shown to induce gene mutations and chromosome aberrations which are known to be involved in the process of carcinogenesis. The induction of secondary cancers is ...

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ژورنال

عنوان ژورنال: Science

سال: 1972

ISSN: 0036-8075,1095-9203

DOI: 10.1126/science.175.4018.200